藤原ここあによるマンガ『妖狐×僕SS』のテレビアニメ化。監督は「侵略!? イカ娘」「ベン・トー」などで演出と絵コンテを担当した津田尚克、シリーズ構成・脚本は「トワノクオン」の根元歳三、シナリオ・設定監修は「STEINS;GATE シュタインズ・ゲート」で監督を務めた佐藤卓哉、キャラクターデザイン・総作画監督は「THE IDOLM@STER アイドルマスター」「たまゆら~hitotose~」の飯塚晴子。
白鬼院凜々蝶(しらきいんりりちよ)が実家を出て入居したのは、シークレットサービス(SS)つきの最高級マンション「メゾン・ド・章樫(あやかし)」だった。凜々蝶には御狐神双熾(みけつかみそうし)がSSとして付くことになるが、双熾は彼女に「僕を貴女の犬にして下さい」と懇願する。「妖館(あやかしかん)」の異名を持つこのマンション、実は妖怪の“先祖返り”である人間たちが住む妖しいマンションだった。
Ririchiyo Shirakiin is the sheltered daughter of a renowned family. With her petite build and wealthy status, Ririchiyo has been a protected and dependent girl her entire life, but now she has decided to change all that. However, there is just one problem—the young girl has a sharp tongue she can't control, and terrible communication skills.
With some help from a childhood friend, Ririchiyo takes up residence in Maison de Ayakashi, a secluded high-security apartment complex that, as the unsociable 15-year-old soon discovers, is home to a host of bizarre individuals. Furthermore, their quirky personalities are not the strangest things about them: each inhabitant of the Maison de Ayakashi, including Ririchiyo, is actually half-human, half-youkai.
But Ririchiyo's troubles have only just begun. As a requirement of staying in her new home, she must be accompanied by a Secret Service agent. Ririchiyo's new partner, Soushi Miketsukami, is handsome, quiet... but ridiculously clingy and creepily submissive. With Soushi, her new supernatural neighbors, and the beginning of high school, Ririchiyo definitely seems to have a difficult path ahead of her.