ミステリコミックの代表作とも呼べる青山剛昌の原作が、お茶の間を賑わす国民的アニメに。頭脳明晰な高校生探偵・工藤新一はとある事件に巻き込まれ、犯罪組織の手によって口封じのため薬品を飲まされる。その作用により彼は、幼児のように体が縮んでしまった。組織の追撃を逃れるため、また元の姿に戻るために江戸川コナンと名乗って正体を隠した新一は、幼なじみの蘭やその父のヘボ探偵と共に暮らしつつ、数々の難事件を解決していく。
Shinichi Kudo is a 17-year-old high school detective whom people call the "Modern Sherlock Holmes." However, one night after a date with his childhood sweetheart Ran, Shinichi witnessed an illegal trade and was knocked unconscious and fed a drug that was supposed to kill him... but he woke up and found himself shrunken to a 7-year-old. In order to track down the men who did this to him, Shinichi reinvented his identity as Conan Edogawa and lived with Ran, whose father happened to be a hopeless detective, and with that came a series of murders and mysteries that he must solve